Godlike:
127 Orgulla (XS2) vs 28 Van (TotA) - Tricky. They both have pretty ridiculous durability, so this will take awhile... kneejerk, I suppose, since Orgulla is pretty fast, which would translate very well to fighting Van and dodging more of his attacks.
Heavy:
126 Garland (FF9) vs 72 Mithos (ToS)
201 Garai (CC) vs 211 Georg (Suikos)
36 Surt (VP1) vs Sync (TotA)
Middle:
229 Viconia (BGs) vs 160 Tear (TotA) - Noticed this didn't have any votes, hence the post. BG is a headache since the good dueling spells are rather different from the spells that are good in-game... I don't really have any respect in the DL for spells with a longer casting time than ~2 or so due to the ease of spell disruption. Of course, Tear runs into the same problem. If they simply physicaled each other, I'd be inclined to vote Tear... but Viconia can buff her own Strength to 18/00 and offer a big bonus to her THAC0. Arguably, she can also inflict slow on Tear with Dolorous Decay and run around the arena away from her while she slowly gets drained, since they're both from games with free movement. Normally Viconia's physical is pretty bad due to only one attack a round, but with the slow and the damage boost? She might just win the slapfight. Except now I remember that BG2 is the game of everyone having 16+ Con, including your hero if you're smart, making Viconia's HP kinda meh even though she's a cleric (nigh equivalent to Mage Nalia, and worse than Thief/Mage Imoen! At least under core rules. Viconia does fare better with max HP per level up.). And I do respect Tear's physical game.
35 Marcy (CC) vs 91 Beatrice (WA3)
Light:
152 Mel (S3) vs 111 Garet (GS)
48 Nicolus (SO2) vs 29 Fargo (CC)
198 Gadget Z vs 34 Zegai
46 Reis (FFT) vs 209 Serra (FE7) - Counters, I guess?