Super: Wait, that doesn't make sense... *checks* Oh. It's the effect of Level 20 Myrrh. So guess it depends on if you agree with that.
The difference is 14.36 and 14.28 for average Res between L20 Myrrh and your own numbers. It makes no difference in Seth's durability that would matter. It is 79% Mdur either way.
Ryu (BoF3) vs Killer (SH3): I think he goes first. Worst comes to worst Feather Sword and some weaker armor.
Kartikeya (WA5) vs Tidus (FFX): I guess Tidus could have some argument but I kinda doubt it.
Ramirez (SoA) vs
Raquel Applegate (WA4): Heals enough? I don't know if that will work though to be honest.
Zio (PS4) vs
Kefka Palazzo (FF6): Good enough on damage to bridge the durability difference.
Heavy
Geno (SMRPG) vs Demi (PS4): Whirl doesn't seem like your everyday variety of magic ID.
Luc (Suikos) vs
Naoto Shirogane (P4): Neither game uses Mdef as status res that I know of.
Bowie (ShF2) vs
Delita Hyral (FFT): Flat out outstats. Temp scaling makes Delita happy (except when he wants the blockers).
Hiro (Lunar:EBC) vs Bosch (BoF5): Massive damage vs. BoF5 boss. I remember this!
Middle
Adell (Disgaea 2) vs Jennifer (Disgaea): Just outstats.
Mizuki (S4) vs Amarant Coral (FF9): I don't think he can deal with the speedy 2HKO.
Jibril (SO2) vs Tio (G2): This fills me with RAGEEEEEEEEEEEEE.
Yukiko Amagi (P4) vs Halley Branckett (SH1): Not sure. Caught between Monkey and Snow.
Light
Vinsfeld Rhadamanthus (WA2) vs Hervey (S4): Insert joke about PURE IDEALS.
Karn (BoF1) vs Edward Damcyan (FF4): Not Edward.
Seth (FE8) vs
Serph (DDS): Serph's magic damage is at least good enough for this.
Mogu (BoF1) vs
Shiba (S3): Not Mogu.