Noting that I have no idea how Isolde works:
- TimeEclipse does allow for some obscene QUI stat debuffing, and it's worth noting that stat downs and status in SaGa are clearly segregated. That said, some bosses and enemies do seem to resist/immune stat downs as well (this is not well documented, shock shock).
If TimeEclipse works on Isolde, I think Blue has the match in the bag because it allows for tripleturns to happen. This is kinda questionable but reasonably arguable, of course, and I detailed why before.
- How badly does Isolde kill Blue from a single attack? SoulRune raises all stats by 50% with quite a meaningful impact, so if it reduces the margin from OHKO to not-OHKO it ups his rate to double and damage significantly (plus status resist odds, yadda yadda). Same question goes for Silence odds on one hit.
The main matter is how much Isolde's damage piles up as he lets her get turns. She doesn't OHKO him straight off in a single, but she piles up timed cards that inflict damage and go off independently from her own turns that pile up pretty brutally along with adding up to break, which makes Blue lose turns and suffer ITD increased damage if he suffers damage while he's stunned (Grand Gaze should be a Break 2HKO, and she can pile multiple of them - and it can inflict Slow on him, which makes him instantly lose, that makes people 1/3 average speed). Also, I actually looked up and Grand Gaze doesn't -actually- have an element attached to it. SoulRune is an interesting point, since it -should- lower her odds of statusing (MK magical status -does- check MDef). The issue I see with using SoulRune, though, is that it gives her a free turn to get started if PP spamming gets her into 75% HP range, and even at full HP, Grand Gaze bullshit getting started is very dangerous - not to mention she can also debuff his MDef with perfect odds while still inflicting damage, and she should 2HKO post-Baxim Bite with a single Grand Gaze card. Still feel Blue's best bet is trying to get off BoundShot Shadow Servant while disallowing Isolde from even a single turn, since the independence of Isolde's pressure is pretty dangerous to Blue, who has no real answer to timed cards in the longer term.
EDIT: And after looking it up further, ShadowServant just straight doubles damage. Yeah, think that strategy works as long as you see at least Grand Gaze being hit by Psychic Prison, which I'm willing to buy. Don't think I'd see it dealing damage (no indication that MK enemies even -use- SP? Yeah. There's SP draining in-game on both ends, but enemies just have infinite SP pools from all I can gather from empiric experience), but thinking the 66% threshold still works for now.