Heavy
Largo (Tales of the Abyss) vs Georg Prime (Suikoden V)
The physical god-general with OK listing no spells. Wrong choice.
Gangrel (Fire Emblem: Awakening) vs Eirika (Fire Emblem: The Sacred Stones)
Eirika has hugely overkill accuracy - part of this is FE8 enemies failing, sure, but even beyond that, it's like +30 over average with Sieglinde @135 adjusted Hit. Higher move makes me inclined to tiebreak for her despite Gangrel's range advantage.
Middle
Lucca Ashtear (Chrono Trigger) vs Fred Maximillian (Suikoden III)
Nowi (Fire Emblem: Awakening) vs Bow (Breath of Fire II)
On one hand, Nowi fails forever at making progress against Bow's healing. On the other hand, Dhyer's BOF2 topic (which should be added to the Alphabetical list of stat topics!) has Shot at a really crappy hit rate (~30%) AND guesses it's resisted by Luck, and Nowi has excellent Luck. And Bow's attack is listed as being very sensitive to defense, which is Nowi's best stat and it's subtractive. It's not really clear if Bow can do anything here. Nowi 3HKOs, so she forces healing every 3rd turn. Bow has 12 shots of healing. That gives him ~25 Shot attempts or so (with occasional misses on both sides and occasionally Nowi ATB doubles). So... he needs to have 6% odds of ID on Shot or better to win semi-consistently. Wow, this fails. I guess I'll see Shot as that good here.
Luke fon Fabre (Tales of the Abyss) vs Sheena Fujibayashi (Tales of Symphonia)
2 fighters each who have interp calls go at each other! Super-regen for Luke not mattering that much, though, I suspect Sheena wins with her combo regardless and loses without it regardless. Probably Sheena, but will await Pyro.
Rena Lanford (Star Ocean: The Second Story) vs Mog (Final Fantasy VI)
Light
Fredrick (Fire Emblem: Awakening) vs Edward Chris von Muir (Final Fantasy IV)
FF4o Edward.
Gogo (Final Fantasy VI) vs Summoner (Bravely Default)
For the record, I'm not a fan of the "hacked the game to have a solo Gogo" interp that sticks him in Light, but it'd be really stupid to have him crush Light, so. Summoner will Default 3 times (easy against Gogo's crappy damage) then unload 4x Susano-o -> 4x Susano-o. That's 10.4K damage to my preferred killpoint of 14.3K, or .72 PCHP per Brave blast. Can Gogo heal himself up enough with nonsense elemental rod healing shenanigans to survive those two blasts? If he can, he wins, if he can't, he loses.
Igrene (Fire Emblem: The Sealed Sword) vs Thief (Final Fantasy Tactics)
Since Tide didn't specify a gender (boo hiss) and I don't think transgender thief is a valid character myself (it's a legit downside to Thief hype in-game), I'm gonna go with the stat topic default which is female Thief. Which means no Steal Heart, and Steal Weapon isn't even that useful vs. FE characters and their handy backups. RIP.