I haven't finished checking out all that interested me in the fall lineup, but here's what I've seen so far.
Chaos;head- Easily my favorite so far. Take K1 out of Higurashi and plop in Satou from Welcome to the NHK, and put them in high school in Tokyo and you have Chaos;head. Twisted, sometimes funny, good creepy vibe and I CAN'T GET THE DAMN ED OUT OF MY HEAD.
Kemeko DX- Twisted humor, thoroughly slapstick. It out-GAINAXes the GAINAX show of the season. More Gainax references (and a SZS) references than you can shake a stick at, appliance inspired robot designs, and off the wall comedy. Basically, a girl from space comes down and declares herself a kid's bride. This girl happens to be about 3 feet tall, built like a trash can, vaguely resembles a pair of testicles, wears Asuka's plug suit and wields a mini-gun. The girl turns out to be a robot suit called Kemeko, and of course, out pops a 6 foot tall standard anime hottie. Hilarity ensues.
Aru Majitsu no Index- My second favorite show of the season so far. Standard shounen type show with some excellent worldbuilding and style. A great tit-for-tat fight scene in episode 2 rocked the house, and there's a girl called Railgun that shoots coins at Mach 3. Can't lose! Faltered a bit in Ep 3, but hopefully will recover.
Ga-Rei Zero- Only watched Episode 1, but liked what I saw. Have to say, DID NOT EXPECT THE ENDING OF THE EPISODE AT ALL. I have to watch the second. It featured motorcycle-fu, where a girl named Natsuki with long straight purple hair used a motorcycle instead of her legs to kick shit while she rode on the back of it. Great production values.
Toradora!- Holy shit, a Rie Kugimiya vehicle I like! Hell must hath frozen over. A love... square? Pentagon? RomCom to the core, but a lot more sedate than stuff like Zero no Tsukaima. Very well done, all around so far. Gets the confessing out of the way early. Taiga >>>>>>*Infinity Louise and Nagi. Ugh.
Shikabane-Hime: AKA- Total GAINAX action show. Feels like the team that made Ep 5 of FLCL went "Hey, what if we made a whole series like this?" Over-the-top action in a good way, but not quite as far as TTGL. Keeps within it's genre for now, but I only watched Episode 1.
Kannagi- Amusing little show. Should be watched for it's gorgeous animation quality alone. Nice and quirky and a good cool-down from shows like Ga-Rei 0.
Hyakko- Standard slice of life show 556. Mostly meh. Next.
Still haven't seen any of:
Mouryou no Hako- Creepy yuri show! Have been in a real comedy mood lately, so the shows like this, Ga-Rei and the next one I'll talk about have waited. Really need to watch. Supposedly one of the best of the season.
Kurozuka- Another creep-factor show. No yuri I'm aware of, but also supposed to be really good. Feels supernatural-detectivey.
Michiko to Hachin- Pyro liked it. I'll give it a shot.
Cassern Sins- Never was much of a Cassern fan, but I may check it out.
No interest in:
Tytania- I normally like space-opera, but haven't heard the best of reviews so I'm steering clear with this much on my plate.
Tales of the Abyss- Heard good things, but playing the game instead.
Yorazura Quartet- Yawn.
Nodame Cantible- Yawn!
Clannad- YAWN!
Linebarrels of Iron- I don't think I can say it better than Zac of ANN.
http://www.animenewsnetwork.com/fall-2008-preview/2008-10-04/zacVampire Knight Guilty, Rosario+Vampire S2- NO.