Heavy
Edge Eblan (Final Fantasy IV) vs Victini (Pokémon) - Status is never a Pokemon's friend.
Light
Laguna Loire (Final Fantasy VIII) vs Larsa Ferrinas Solidor (Final Fantasy XII) - Hahahaha. Exactly what Laguna needs. Some light damage to let him get into Limit range and start spamming.
Can't vote on it, but on Smeargle, the more balanced thing to do would be limit him to only common/TM/HM moves. Still gives him a hilarious stalling game in, say, Toxic/Rest/Protect/(other), but is also relatively easy to do in-game. Basically a nice middle ground between the ridiculous and the Puny that he becomes with the other interps.